Mad City Labs

  • Mad City Labs Nano-View: A fully integrated positioning system for use with inverted optical microscopes

    Mad City Labs Nano-View: A fully integrated positioning system for use with inverted optical microscopes

    The Mad City Labs Nano-View® is a fully integrated positioning system for use with inverted optical microscopes. The Nano- View® combines a long range, motor driven, two axis, linear motion stage with an ultra-low profile, high resolution piezo nanopositioning system.

  • Mad City Labs:    Application of Picometer Resolution - Direct Measurement of Calibration Standard

    Mad City Labs: Application of Picometer Resolution - Direct Measurement of Calibration Standard

    3D representation of Si (111) atomic steps measured by AFM.

    Position noise is critical to the resolution of many applications including Atomic Force Microscopy (AFM). Mad City Labs metrology-class picopositioners™ can be used to build high resolution AFM systems that can detect picometer-scale features. Accurate measurements of single atomic steps in Silicon (111), shown to the left, demonstrate the capabilities of an AFM built with Mad City Labs picopositioners™. The measurement of atomic steps in Silicon (111) is a direct measurement of an established calibration standard. Additional AFM performance demonstrations are available.

  • Mad City Labs PicoQ Sensors are superior to capacitive Sensors

    Mad City Labs PicoQ Sensors are superior to capacitive Sensors

     Nano-METZ position noise power spectrum showing flat response at low frequencies with position noise floor of 400 femtometer/√Hz. 

    Mad City Labs' implementation of our exclusive PicoQ® sensor technology minimizes position noise for the best positioning resolution in the industry. Our high performance stages have moved beyond the realm of nanopositioning into picopositioning, leaving former competitors behind. Legacy capacitive sensors cannot achieve picometer resolution. The position noise power spectrum of the Nano-METZ is shown below left. Positioners with PicoQ® senorsexhibit noise floors in the femtometer/√Hz range and positioning resolution in the picometer range. Below right is a plot of the Nano-HS3M performing a 20 picometer peak-to-peak sine wave using the 20 bit DAC in the Mad City Labs USB interface, while the sensor is being rmeasured by the 24 bit ADC. The least signficant bit of the DAC is 5 picometers, and is clearly resolvable. Legacy capacitive sensors cannot measure anything at this level. Our competitors cannot produce similar data.

  • Don't just Think Nano, Think Pico!: Mad City Labs improves proprietary PicoQ sensor technology

    Don't just Think Nano, Think Pico!: Mad City Labs improves proprietary PicoQ sensor technology

    Nano-METZ: a compact z-axis nanopositioning system designed for high speed scanning and ultra-low noise characteristics for demanding AFM and metrology applications. Featuring Mad City Labs proprietary PicoQ® sensor technolog® sensor technology

    Mad City Labs has improved the implementation of their proprietary PicoQ® sensor technologyin order to minimize position noise for the best ever positioning resolution in the industry. As a result, their high speed, high performance stages with short travel range have moved beyond the realm of nanopositioning into picopositioning, leaving former competitors behind. Systems with so-called "high performance" capacitive sensors cannot achieve picometer resolution because of rising 1/f noise at low frequencies. The position noise power spectrum of the Nano-METZ is shown below. Nanopositioners and picopositioners with PicoQ® sensors have a relatively flat position noise power spectrum at low frequencies and do not exhibit 1/f noise down to 0.001 Hz.

  • Nature Protocols Paper on Mad City Labs MicroMirror TIRF System

    Nature Protocols Paper on Mad City Labs MicroMirror TIRF System

    Nature Protocols has published a paper from researchers at the University of Wisconsin-Madison and Brandeis University about the colocalization single-molecule spectroscopy (CoSMoS) method for studying cellular machines using the Mad City Labs MicroMirror TIRF system.

    The technique of micro-mirror TIRF (total internal reflection fluorescence) microscopy is the only proven method to study the ordered assembly and function of multi-component biomolecular machines. The Mad City Labs' MicroMirror TIRF system is part of a single molecule imaging instrument portfolio and draws on Mad City Labs expertise with high precision, high stability nanopositioning systems and microscopy solutions.

  • Mad City Labs Low Cost Microscopy Solutions

    Mad City Labs Low Cost Microscopy Solutions

     

    Mad City Labs recently introduced two new, low cost microscopy solutions. The MCL-MOTNZ motorized XY stage with piezo Z and MCL-MANNZ manual XY stage with piezo Z are compatible with major third party microscopy and instrumentation control software including LabVIEW, Nikon Elements, Metamorph, ?Manager, SlideBook, and Image-Pro. 

    The MCL-MOTNZ is a value priced positioning system for use with inverted optical microscopes. The MCL-MOTNZ combines a stepper motor XY linear motion stage with a closed loop, high resolution, Z-axis nanopositioning system. The micropositioning stage provides 25 mm of travel per axis with a minimum step size of 95 nm. The use of high precision components and our proprietary intelligent control technique results in an ultra-stable microscope platform with excellent native precision without the addition of costly encoders. The innovative sample holder design together with the ultra-low profile of the piezo Z stage makes sample exchange and sample loading quick and straightforward.

  • New Metrology products from Mad City Labs

    New Metrology products from Mad City Labs

    Mad City Labs recently expanded its line of nanopositioning systems for metrology applications with several high speed, high stability, low position noise, picometer precision products. 

    The Nano-HS3M (shown above) is a high speed, XYZ precision nanopositioning system with picometer positioning resolution. Other new products in the line include the Nano-METZ, a compact z-axis nanopositioning system designed for high speed scanning and ultra-low noise characteristics for demanding AFM and metrology applications; the Nano-MET2 and Nano-MET3, ultra-low noise, high precision nanopositioning systems with picometer positioning resolution; and the Nano-MET10 and Nano-MET20, compact, single axis nanopositioning systems with exceptional resonant frequency and low noise characteristics.

  • Mad City Labs: RM21 Microscope platform for the future

    Mad City Labs: RM21 Microscope platform for the future

     

    Mad CIty Labs' RM21™ is a precision aligned microscope platform for epifluorescence microscopy. The RM21™ has been designed for maximum user accessibility. This feature offers users the opportunity to develop flexible configuration microscopy instruments with ease. It has been manufactured with high precision to allow easy alignment of microscopy and optical components within its three dimensional space. In addition, all posts and fixturing points are referenced to a known datum. With a robust design, precision manufacturing and assembly, the RM21™ is the ideal platform for a range of microscopy applications such as super resolution (SR) microscopy, fluorescence microscopy and TIRF.

  • Mad City Labs

    Mad City Labs

    Mad City Labs, Inc is a leading manufacturer of flexure based nanopositioning systemscapable of sub-nanometer positioning resolution.